A 2016 phase 1–2 prospective study orally administered 800 mg per day to 27 patients with telomere diseases. The primary efficacy endpoint was a 20% reduction in the annual rate of telomere attrition measured. Toxic effects formed the primary safety endpoint. The study was halted early, after telomere attrition was reduced in all 12 patients who could be evaluated. 12 of 27 patients achieved the primary efficacy end point, 11 of whom increased telomere length at 24 months. Hematologic responses (secondary efficacy endpoint) occurred in 10 of 12 patients who could be evaluated at 24 months. Elevated liver-enzyme levels and muscle cramps (known adverse effects) of grade 2 or less occurred in 41% and 33% of the patients, respectively. 
Trenbolone is without a doubt one of the most beneficial anabolic steroids on the market. When we consider the therapeutic benefits of Nandrolone, or even Testosterone, it may not quite match up but on the basis of raw power and physique transformation Trenbolone Acetate is the king. No steroid will be as beneficial when cutting, not even close, and when bulking it is nothing short of fantastic. While Tren is beneficial during cutting and bulking phases, if you’re only going to use it in one phase always choose cutting. Many will actually need to limit their Trenbolone Acetate use to one phase due to the harshness of the compound in some men, especially when we consider cardiovascular strain. However, solid responders who are in excellent health should find they can use the steroid during both phases with a high level of success.