However, in December 2004 the United States the 14-member Food and Drug Administration (FDA) advisory committee, plus voting consultants, for Reproductive Health Drugs unanimously rejected Procter and Gamble's fast-track request for Intrinsa citing concerns about off-label use . In Canada, post-menopausal women have been able to obtain government-approved testosterone treatment since 2002. In Australia, post-menopausal women can use Organon testosterone implants which have to be surgically inserted and last from three to six months. 
Potential side effects are different between men and women. Common effects seen in men is jaundice, baldness, acne, breast tissue development, permanent liver damage and/or liver tumors and heart problems. Common side effects for women include jaundice, permanent deepening of their voice, increased facial hair, acne, permanent liver damage, heart problems and problems with their menstrual cycle. This list is not exhaustive, there are several other short and long-term side effects that are caused by steroid use. Most of the effects will gradually get better after cessation of the drug. However, there are grave and permanent risks involved whether the anabolic steroid is taken orally or with an injection.